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Please use this identifier to cite or link to this item: http://hdl.handle.net/123456789/1320

Title: Comparison of Ivermectin and Benzyl Benzoate Lotion for Scabies in Nigerian Patients
Authors: Sule, Halima M.
Thacher, Tom D.
Issue Date: 2007
Publisher: American Journal of Tropical Medicine and Hygiene
Series/Report no.: Vol. 76;No. 2; Pp 392–395
Abstract: Few studies have compared ivermectin directly with topical agents in developing countries. We compared the effectiveness of oral ivermectin (200 g/kg) with topical 25% benzyl benzoate and monosulfiram soap in 210 subjects of age 5 to 65 years with scabies. Subjects with persistent lesions after 2 weeks received a second course of treatment. All lesions had resolved after 2 weeks in 77 of 98 (79%) subjects treated with ivermectin and in 60 of 102 (59%) subjects treated topically (P 0.003). The improvement in severity score was greater in the ivermectin group than in the topical treatment group (P < 0.001). The overall cure rate after 4 weeks was 95% in the ivermectin group and 86% in the topical treatment group (P 0.04). Compared with topical benzyl benzoate and monosulfiram in the treatment of scabies, ivermectin was at least as effective and led to more rapid improvement.
URI: http://hdl.handle.net/123456789/1320
Appears in Collections:Family Medicine

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