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Title: Effects of Cucumis metuliferus E Mey. Ex Naud (Cucurbitaceae) Fruit Extract on some Male Reporoductive Parameters in Adult Rats
Authors: Wannang, Noel N.
Jimam, Nanloh S.
Gyang, Steven S.
Bukar, Bukata B.
Gotom, Saleh
Keywords: sperm count
sperm viability count
Issue Date: May-2008
Publisher: African Journal of Pharmacy and Pharmacology
Series/Report no.: Vol. 2;No. 3; Pp 048-051
Abstract: The effect of the extract of Cucumis metuliferus fruit on some male reproductive parameters was investigated in albino rats. The LD50 of the extract was above 5000 mg/kg body weight when administered orally. Histological studies showed that there was no remarkable change in the testes histology compare to the control. The effects on sperm cells showed a statistically significant (P<0.05) increase in total sperm count with an insignificant (P>0.05) increase in viability count in rats treated with 500 mg/kg dose point. On the other hand, 1000 mg/kg dose point produced significant (P<0.05) decrease in total sperm count and viability count compare to control. This result suggests that C. metuliferus fruit extracts could be beneficial in increasing sperm/semen integrity.
URI: http://hdl.handle.net/123456789/1528
ISSN: 1996-0816
Appears in Collections:Pharmacology

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