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|Title: ||Effects of Cucumis metuliferus E Mey. Ex Naud (Cucurbitaceae) Fruit Extract on some Male Reporoductive Parameters in Adult Rats|
|Authors: ||Wannang, Noel N.|
Jimam, Nanloh S.
Gyang, Steven S.
Bukar, Bukata B.
|Keywords: ||sperm count|
sperm viability count
|Issue Date: ||May-2008|
|Publisher: ||African Journal of Pharmacy and Pharmacology|
|Series/Report no.: ||Vol. 2;No. 3; Pp 048-051|
|Abstract: ||The effect of the extract of Cucumis metuliferus fruit on some male reproductive parameters was investigated in albino rats. The LD50 of the extract was above 5000 mg/kg body weight when administered orally. Histological studies showed that there was no remarkable change in the testes histology compare to the control. The effects on sperm cells showed a statistically significant (P<0.05) increase in total sperm count with an insignificant (P>0.05) increase in viability count in rats treated with 500 mg/kg dose point. On the other hand, 1000 mg/kg dose point produced significant (P<0.05) decrease in total sperm count and viability count compare to control. This result suggests that C. metuliferus fruit extracts could be beneficial in increasing sperm/semen integrity.|
|Appears in Collections:||Pharmacology|
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