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|Title: ||Hemoglobin and Serum Iron Concentrations in Menstruating Nulliparous Women in Jos, Nigeria|
|Authors: ||Mary-Jane, N.|
Nnanna, Ogbonnaya U.
Okolie, Charles E.
Odewumi, Lolade A.
Isiguzoro, Ikechukwu O. U.
Lugos, Moses. D
|Issue Date: ||2013|
|Publisher: ||Laboratory Medicine|
|Series/Report no.: ||Vol. 44;No. 2; Pp 121 - 124|
|Abstract: ||Background: Low hemoglobin (Hb) and iron deficiency among child
bearing females have been linked to decreased immune system
function, impaired cognitive functioning and complications in
Methods: A total of 106 blood samples from apparently healthy
nulliparous female students were assayed for Hb and serum iron
concentrations using the cyanmethemoglobin and bathophenanthroline
methods, respectively, to evaluate changes that may occur in these
parameters at different phases of the reproductive cycle.
Results: The mean (SD) Hb values during the ovulatory, menstrual,
and follicular phases were 13.27 (1.14) g/dL, 12.05 (1.31) g/dL, and
12.23 (1. 56) g/dL, respectively. The prevalence of anemia (Hb<12
g/dL) was reported among 21 (19.8%) subjects, and 31 subjects
declined to complete their samples collection. The mean serum
iron concentrations during the 3 phases were 92.98 (18.25) μg/dL,
79.90 (13.14) μg/dL and 70.85 (18.65) μg/dL, respectively. A total of
28 (26.4%) study participants showed iron deficiency (serum level,
<65 μg/dL). These variations in the values of Hb and serum iron
concentrations were statistically significant in the 3 phases. However,
no significant difference was observed in Hb concentrations between
the menstrual and follicular phases. Of interest, a positive correlation
was observed between the hemoglobin and serum iron concentrations
within the phases, with the exception of a few cases that showed
Conclusion: Menstruation has been shown to be the major cause of
anemia and iron deficiency in nulliparous women. A prophylactic dose of
iron and folate supplements may be indicated for menstruating females
to cushion the adverse effects of menstruation on hematologic status.|
|Appears in Collections:||Medical Laboratory Sciences|
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