University of Jos Institutional Repository >
Medical Sciences >
Please use this identifier to cite or link to this item:
|Title: ||Profile of Infective Endocarditis in Nigerian Children|
|Authors: ||Ige, O. O.|
Yilgwan, C. S.
Akhiwu, H. O.
|Keywords: ||congenital heart disease infective endocarditis|
rheumatic heart disease
|Issue Date: ||2017|
|Publisher: ||Journal of Advances in Medicine and Medical Research|
|Series/Report no.: ||Vol.22;Iss.8: Pp 1-9|
|Abstract: ||Background: Infective endocarditis (IE) was initially thought to be uncommon in children but is on
the increase due to improved cardiac services in the developing world.
Aims: Aims of this study is to describe the profile of IE in children in Jos, Nigeria and identify the
peculiarities of the disease in the locality.
Methods: Case records of children diagnosed with IE based on the modified Duke’s criteria over a
seven year period were retrospectively reviewed in a tertiary hospital. Their clinical manifestations,
blood culture isolates, presence or absence of vegetations and clinical outcomes were
documented and analyzed using Epi Info 7.
Results: Case records of thirty children were reviewed. The number of children managed
increased yearly with 10 (33.3%) of them seen in the last year of the study. The clinical features
were mainly non-specific - fever (70.0%), congestive cardiac failure (63.3%) and anorexia (63.3%)
being the major findings. Staphylococcus aureus was the commonest isolate, present in 5 (45.5%)
of the 11 blood culture-positive cases. Other organisms isolated were Klebsiella species in 3 (27.3%), Pseudomonas aeruginosa in 2 (18.2%) and Acinetobacter baumami in 1 (9.1%) child.
Vegetations were detected in 12 (40.0%) children, most of them located on the mitral valve.
Mortality occurred in 8 (26.7%) children and was significantly higher in males – P = 0.02.
Conclusion: There is a marked increase in the number of children admitted and managed for IE in
the last year of the study possibly due to an increased index of clinical suspicion of IE. A high index
of suspicion is required for diagnosis because many children presented with nonspecific clinical
|Appears in Collections:||Paediatrics|
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.