|
University of Jos Institutional Repository >
Pharmaceutical Sciences >
Pharmacology >
Please use this identifier to cite or link to this item:
http://hdl.handle.net/123456789/229
|
| Title: | Anti-Ulcer Properties Of Alkaloids Isolated From The Fruit Pulp Of Cucumis Metuliferous (Curcurbitaceae) |
| Authors: | Omale, S
Auta, A
Wuyep, N.N
Wannang, N.N |
| Keywords: | Cucumis Metuliferous,
Cucurbitaceae,
Ulcerogenic,
Haemorrhages |
| Issue Date: | 17-Sep-2011 |
| Publisher: | International Journal of Pharmaceutical Sciences and Research |
| Citation: | Pp 2586-2588 |
| Series/Report no.: | Vol.2;No.10 |
| Abstract: | Anti-ulcer properties of the alkaloids isolated from the fruit of Cucumis metuliferous was investigated in mice. Ethanol-induced gastric lesion was used to assess the anti-ulcer activity. In this study, there was a significant (p<0.05) decrease in haemorrhages and ulcerations of the gastric mucosa at 500 and 1000 mg/kg of the alkaloid compared with control. The activity of the extract is comparable to that of the standard control group administered ranitidine (1 mg/kg). The alkaloids of C. metuliferus showed a demonstrable potential as an anti-ulcer agent that could be used for the treatment of peptic ulcer disease. |
| URI: | http://hdl.handle.net/123456789/229 |
| ISSN: | 0975-8232 |
| Appears in Collections: | Pharmacology
|
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.
|
