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Please use this identifier to cite or link to this item: http://hdl.handle.net/123456789/230

Title: Antiviral Activity of the Fruit Extract of Cucumis metuliferus E. Meye (Curcubitaceae) in Chicks
Authors: Wannang, Noel N.
Ede, Samuel O.
Kwanashie, Helen O.
Keywords: Alkaliods.
Cucumis metuliferus.
Newcastle disease.
Antiviral Property
Issue Date: 2010
Publisher: African Journal of Basic and Applied Sciences
Citation: Pp 89-93
Series/Report no.: Vol.2;No.3-4
Abstract: Aim of Study: Antiviral property of the alkaloidal components of fruit extract of Cucumis metuliferus E. Meye (100-600 mg/kg) was evaluated in chicks infected with newcastle disease. Materials and Method: The alkaloidal component of the fruit extract was investigated for antiviral properties in chicks. The birds were infected with a virulent strain of newcastle disease virus and the following were examined: physical signs of clinical illness, time of death and histopathological examination of the culprit organs of infection (proventriculus, ventriculus and caecum) and compared with control groups. Results: The result showed that the alkaloids isolated from the plant material were capable of reducing and/or reversing the effects of the virus in chicks. Conclusion: The study showed that the alkaloidal component of this fruit is a potent antiviral agent since it prevented and reversed virus induced manifestations in infected chicks.
URI: http://hdl.handle.net/123456789/230
ISSN: 2079-2034
Appears in Collections:Pharmacology

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