Distribution of Herpes Simplex Virus Type 1 IgG Antibodies in Kaduna Metropolis

Abstract

This study was to determined the prevalence rate of herpes simplex virus type-l in Kaduna Metropolis. Herpes simplex virus type 1 causes vesicular lesions of the oral mucosa can also cause clinical diseases including the genitalia, liver, lung, eye, and central nervous system which may be severe, particularly in the setting of immunosuppression. Forty (40) to 85% of all Africans carry the antibodies to HSV- 1. Between 10 to 20% of that population suffer recurring outbreaks. There is very little public awareness of Herpes in Kaduna State, Nigeria. Three hundred and eighty four (384) samples were collected and analyzed using commercial ELISA kit obtained from institute virion/serion GmbH Germany.The analysis was carried out according to the manufacturer s instruction, and the result read at 450nm and 630nm using Sigma Diagnostic EIA multi-well reader II. Of the 384 samples tested 381 (99.2%) were anti- HSV-1 positive. The male were 226 with 99.1 % and female 158 with 99.3 anti- HSV-1 seropositive. In this study, it can be seen that HSV-1 was found to be 99.2% meaning that HSV-1 is highly endemic in Kaduna State, Nigeria.