Effect of Coconut Oil, Coconut Water and Palm Kernel Oil on Some Biochemical Parameters in Albino Rats

Abstract

The coconut oil, coconut water and palm kernel oil was administered orally at a dose of 400mg/kg body weight to white albino rats to check for some effect on biochemical parameters. Twenty (20) rats divided into four (4) groups of five (5) rats each. One group was treated with distilled water and feed only serving as control, second group was treated with coconut water only while the third group was treated with coconut oil only and the fourth group was treated with palm kernel oil only. The treatment lasted for 7 days. Effect of the coconut oil, coconut water and palm kernel oil on lipid profile, glucose and protein were analysed, also toxic effect was determined using biochemical enzyme markers.Treatment showed significant (p<0.05) decrease in glucose and protein levels. Treatment with coconut oil, coconut water showed significant (p<0.05) decrease in Triglyceride, Total cholesterol, LDL while it shows significant (p<0.05) increase when treated with palm kernel oil. Also, treatment with coconut oil, coconut water showed significant (p<0.05) increase in HDL while treatment with palm kernel oil showed significant (P<0.05) decrease.Treatment with coconut oil, coconut water and palm kernel oil showed a significant (p<0.05) decrease in enzyme activities except for ALP when treated with palm kernel oil, ALT when treated with coconut oil. Treatment with coconut oil, coconut water and palm kernel oil showed hypoglycaemic properties and also shows no toxic effect on the liver at the concentration employed.