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Please use this identifier to cite or link to this item:
http://hdl.handle.net/123456789/396
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| Title: | Anticonvulsant Activity of Some N-phenothiazyl and N-Carbazyl Para-Substituted Benzamides |
| Authors: | Afolabi, E.O.
Wannang, N.N.
Gomos, L.P
Iyoryisa, S. |
| Keywords: | Epilepsy,
Seizures. |
| Issue Date: | 2006 |
| Series/Report no.: | Pp 12-18; |
| Abstract: | Some Nphenothiazyl and Ncarbazyl-parasubstituted benzamides were synthesized and evaluated for anticonvulsant
activity in mice against pentelentetrazoleinduced seizures. The study was designed to determine the relationship
between the structure of the benzamides and their anticonvulsant activity. In both series, the chloro- analogues were the
most potent. The study showed that substituted benzamides are potential anticonvulsants. Thus they may be exploited
for therapeutic usefulness in the treatment of epilepsy and seizures. |
| Description: | PROCEEDINGS OF THE NEUROSCIENCE SOCIETY OF
NIGERIA (NSN) CONFERENCE, JOS. |
| URI: | http://hdl.handle.net/123456789/396 |
| Appears in Collections: | Pharmaceutical Chemistry
Pharmacology
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