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University of Jos Institutional Repository >
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Please use this identifier to cite or link to this item:
http://hdl.handle.net/123456789/444
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| Title: | Drug Susceptibility Pattern of Mycobacterium tuberculosis Among Pulmonary Tuberculosis Patients in Jos, Nigeria |
| Authors: | Mawak, J.D.
Gomwalk, N.E
Bello, C.S.S
Kandakai-Olukemi, Y.T |
| Keywords: | tubcrcule bacilli,
resistance,
resistance,
Lowenstein-Jensen medium. |
| Issue Date: | 30-Dec-2006 |
| Publisher: | Nigerian Journal of Experimental and Applied Biology |
| Series/Report no.: | Vol.7;No.2;Pp 129-133 |
| Abstract: | A study designed to determine the drug-susceptibility profile of tubercule bacilli to tirst line anti-tuberculosis
drugs was undertaken in Jos, Nigeria between January 1997 and December 2000. Drug susceptibility
on 35 strains of tubercule bacilli isolated from new tuberculosis patients were performed against isoniazid
(lNH). streptomycin (STM), ethambutol (EMB) and rifampicin (RIF) by the proportion method using
Loweustein-Jensen medium. A total of 34.27% of the isolates/strain were resistant to one or more drugs
tested. Resistance in isoniazid (28.57%) and streptomycin (22.86) were most common common. A
Significant tinding in the study was the low level of resistance to ethambutol (2.86%) and rifampicin
(0.00%). Multi-drug resistance is already a problem in 10s. A continuous monitoring of drug resistance for
planning and assessing the national tuberculosis (TB) control programme is, therefore, indicated. |
| URI: | http://hdl.handle.net/123456789/444 |
| Appears in Collections: | Microbiology
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