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|Title: ||Non Hogdkin Lymphoma Associated With Schistosomaisis? A Case Report and the Significance of Tumour Markers|
|Authors: ||Adisa, James O.|
Egbujo, Ejike C.
Madukwe, Jonathan U.
Silas, Olugbenga A.
Echejo, Godwin O.
Golwa, Filimon H.
Chundusu, Joseph M.
Yahaya, Amina B.
|Keywords: ||colonic tumour|
|Issue Date: ||2012|
|Publisher: ||International Journal of Biomedical and Advance Research|
|Series/Report no.: ||Vol. 3;No. 2; Pp 724-729|
|Abstract: ||We report a case of a possible association of schistosomiasis with Non-Hodgkins lymphoma. A 19
year old Nigerian lady presented with week long history of abdominal swelling and vomiting.
Sonography of the abdominal cavity gave a diagnosis of colonic tumour. Resected portion of the
ileum showed an ileoceacal mass appearing like an intususception. Histopathology initially revealed
schistosomal ova and the adult worm in-copula, Immunohistochemistry however revealed that the
mass was not just a granuloma, but a diffuse B-lymphocyte Non-Hodgkins lymphocytic lymphoma.
The proximity of the schistosoma ova in the tissue sections suggests that schistosomiasis may have
some effect on carcinogenesis. We therefore recommend that patients with chronic parasitic
infestation, especially schistosomiasis, should be monitored more closely in view of the relevant
emerging association between cancer and infections.|
|Appears in Collections:||Medical Laboratory Sciences|
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