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    Development and validation of instrument for assessing patients’ knowledge, attitude, and practice (KAP) on uncomplicated malaria management
    (CrossMark., 2019) Nanloh S. Jimam; Nahlah E. Ismail; Maxwell L. P. Dapar
    Objectives: To develop and validate patients’ knowledge, attitudes, and practice instrument for uncomplicated malaria (PKAPIUM). Material and Methods: A draft PKAPIUM scale was developed after the review of relevant literature and malaria treatment guidelines, and six experts validated its content. Monte Carlo simulation principle was followed in arriving at 300 patients populations whose data were used to reduce the items based on “Kaiser’s eigenevalue-greater-than-one rule.” This was followed by the test of validity and reliability to assess the psychometric properties of the instrument. Results: The items content validity indices (I-CVI) and the scale CVI (S-CVI) using universal agreement (UA) within experts (S-CVI/UA) and average CVI (S-CVI/Ave) approaches were good (0.8–1.00), with absence of items’ floor or ceiling effects. Twenty-one items were retained in the new scale arranged under four factors with average variance extracted (AVE) and square root AVE values of 0.58–0.70 and 0.76–0.84, respectively, suggesting convergent and discriminant validities. The goodness-of-fit results [Chi-square (CMIN/DF) = 3.07, p = 0.00], standardized root mean square residual = 0.070, root mean square error approximation = 0.08 confirmed the hypothesized factor structures of the scale whose internal consistency of Cronbach’s alpha and composite reliability values were 0.74 and 0.82, respectively, and stability of ICC = 0.92 [95% confidence interval : 0.87–0.95, F = 43 (p = 0.51)]. Conclusion: The validity and reliability of the PKAPIUM were in acceptable ranges.
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    PATIENTS’ KNOWLEDGE, ATTITUDES, AND PRACTICES ON UNCOMPLICATED MALARIA MANAGEMENT IN PLATEAU STATE, NORTH-CENTRAL NIGERIA
    (ASIAN JOURNAL OF PHARMACEUTICAL AND CLINICAL RESEARCH, 2019) NANLOH S JIMAM; NAHLAH E ISMAIL
    This study aimed to assess patients’ knowledge, attitudes, and practices (KAP) on uncomplicated malaria management in primary healthcare (PHC) facilities of Plateau state, Nigeria. Methods: A validated self-reported scale known as patients’ KAP instrument for uncomplicated malaria with Cronbach’s alpha reliability of 0.74 was administered to 956 patients that consented to participate in the study across 24 PHC facilities in the state between May and July 2017. The collated data were analyzed using Microsoft Excel and IBM Statistical Package for the Social Sciences (SPSS®) version 23 software. Results: There were more female participants (53.5%) compared to the males (46.5%), and majority (33.4%) within the age range of 28 and 37 years with 26.5% falling within the age range of 18–27 years and children of <18 years of age constituted 13.8% of the study population. About 42.1% of the respondents were married, and many either had secondary (37.3%) or primary (30.0%) education as their highest qualifications. With overall mean (±standard deviation [SD]) attitudes’ score of 34.55 (±7.20), majority (50.8%) were categorized as having average positive attitudes toward disease and its management, and many of them (55.2%) also had good knowledge (mean [±SD] score=4.59 [±1.44]) and practices (67.1%) (mean [±SD] score=14.98 [±3.44]) on the disease and its management. Conclusion: The study indicated respondents’ knowledge and practices on uncomplicated malaria as good, while their attitudes toward the disease
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    EFFECT OF COTRIMOXAZOLE PROPHYLAXIS IN HIV-1 INFECTED PATIENTS ATTENDING JOS UNIVERSITY TEACHING HOSPITAL
    (IJPSR, 2011) K. D. Falang; N. S. Jimam; J. Idoko; M. O. Uguru
    Many chemo prophylactic approaches to manage or prevent opportunistic infections using many drugs have been reported. Based on the reported cases of chemo prophylactic approaches to manage opportunistic infections, the effect of Cotrimoxazole on HIV patients was studied. Seventy two patients with CD4+ cell counts ≤ 350cells/µl were recruited for the study. Each patient received cotrimoxazole two single strength tablets (2 x 480mg) three times a week. The patients were followed for a period of six months during which time data was collected at month 1, month 3 and month 6. The results showed that dermatological, gastrointestinal and respiratory as well as other bacterial related infections were considerably reduced in these patients during the six month period of the study. Being a drug that is cheap, readily available and not requiring any special storage and handling conditions, cotrimoxazole could be considered as a good prophylactic agent in the management of HIV/AIDS disease in resource limited settings such as ours.
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    Prescription patterns of antimalarial medicines in selected primary health care (PHC) facilities of Jos north local government area (LGA) of plateau state, Nigeria
    (European Journal of Biotechnology and Bioscience, 2019) Nanloh S Jimam; Wetkos D Dayom; Micah Y Jingina; Umar D Mohammed
    Objectives: The high prevalence of malaria in sub-Saharan Africa has been linked to irrational treatment practices. The present study evaluates prescription patterns of antimalarial drugs in PHC facilities of Jos North LGA of Plateau state, North-Central Nigeria. Materials and methods: Nine hundred (900) patients’ data were extracted retrospectively using Patients’ Medication Review Form (PMRF), and analyzed using Statistical Package for Social Sciences (SPSS) version 20. Results: Out of 900 patients that were treated for the disease in the selected primary healthcare facilities, majority (61.2%) were female and artemether lumefantrine combination was the most prescribed drug (28.7%) by the prescribers, followed by paracetamol (26.2%) as co-medication. The average number of drugs per prescription was 5.33±0.58 (Mean ±SD). The result indicated irrational prescription practices by the prescribers based on the observed poly pharmacy practices (5.33±0.58 (Mean ±SD)), prescription by generic (66.4%), and inclusion of injectables (18.0%), while their use of antibiotics (21.5%) and prescription from essential drug list were in accordance with the WHO/INRUD optimal levels. Conclusion: The result shows irrational prescription practices in the PHC facilities as there were high practices of poly-pharmacy, poor prescription by generics, and unnecessary inclusion of injectable in patients’ regimens
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    Pharmaceutical care and medication adherence in management of psychosis in a Nigerian tertiary hospital
    (Journal of Research in Pharmacy Practice, 2019-08-03) Jonathan Danladi; Kakjing D. Falang; Raymond A. Barde; Nanlok S. Jimam; Dauda A. Dangiwa; Hafsat O. Jimoh
    The primary objective of this study is to examine the medication adherence (as a function of pharmaceutical care) and its contributing factors in schizophrenic patients receiving antipsychotic drugs. Methods: This was a cross-sectional study administering a structured questionnaire to 231 patients. Adherence was measured through patient self-reporting. Association between independent variables and adherence to antipsychotics were measured through odds ratios (OR) in the univariate analysis while the best predictors of adherence were determined through the multiple logistic regressions. Findings: Adherence level was found to be 65.8% (95% confidence interval [CI]: 59.3-71.9%). The following factors were identified to be associated with adherence in the univariate analysis: age (OR 1.088), sex (OR 1.231), employment (OR 0.366), marital status (singles, OR 0.022), drug adherence counseling (OR 11.641), twice a day frequency (OR 8.434), alcohol non-intake (OR 1.469), educational level (primary OR 1.9312, secondary OR 11.022, tertiary OR 4.771), occupation (public servant 6.273). In the multivariate analysis, age, three times a day frequency of drug intake, singles and educational levels such as primary, secondary or tertiary school, strongly affected adherence (P < 0.05). Conclusion: Although patients adherence level was high (65.8%), there is a need to emphasize that pharmacists spend more time in counseling and educating patients, especially younger ones on drug adherence before any antipsychotic medications are dispensed. Furthermore, patients should be taught the use of adherence devices such as reminders so that adherence to antipsychotic medications can be optimized.
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    Patient factors impacting antiretroviral drug adherence in a Nigerian tertiary hospital
    (Journal of Pharmacology and Pharmacotherapeutics, 2012) Kakjing D.; Falang, P.; Akubaka, N.; Jimam S.
    To study the adherence levels and explore factors impacting them in out-patients on antiretroviral therapy (ART) at the AIDS Prevention Initiative in Nigeria antiretroviral clinic of the Jos University Teaching Hospital. Materials and Methods: We administered a structured questionnaire to 461 patients presenting to the clinic. Adherence was measured using the patient self-report. The association between independent variables and adherence to ART was measured through odd ratios (OR) in the univariate analysis. The best predictors of adherence were determined through multiple logistic regression models with backward elimination. Results: The adherence level was found to be 87.9%. The following factors were found to have strong impact on adherence in the univariate analysis: age (OR 1.04), sex (OR 1.14), employment (OR 1.29), knowledge of HIV (OR 1.11), thrice daily frequency of drug intake (OR 1.68), twice daily frequency (OR 2.18), alcohol no intake (OR 0.29), knowledge of ARVs (OR 1.23), pill burden (OR 1.20), and HIV status disclosure (OR 1.08). In the multivariate analysis, only age, alcohol no intake and twice daily, frequency of drug intake affected adherence (P < 0.05). Conclusions: To increase adherence and the effectiveness of ART, there is need to continuously emphasize the use of adherence devices and reminders. Counseling and adherence education should also be emphasized especially for younger patients and those with low educational levels.
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    Pharmacists’ knowledge and perceptions about herbal medicines: A case study of Jos and environs
    (Wolters Kluwer - Medknow, 2017) Nanloh S. Jimam; Benjamin N. Joseph; Dooshima C. Agba
    Background: Due to increased health consciousness among the public, the use of herbal products are on the increase on a daily basis. To achieve optimal benefits, there is a need for pharmacists who are the custodians of knowledge on drugs and drugs‑related products to have more understanding and interest in herbal medicine for effective counseling on the products. The purpose of this study was to assess Pharmacists’ knowledge and perceptions regarding herbal medicine use. Methods: Self‑administered questionnaires were administered to 200 pharmacists working within the study areas to fill; after which the collected data were statistically analyzed using IBM SPSS software programmer, version 20. Results: Only 88.5% of the respondents responded on the questionnaires, and their mean age was 34 years; median year of experience in practice was 8.2 years; and their areas of practice included hospital (56.1%), community (28.1%), academic (8.47%), and industries (4.52%). More than half (76.27%) of them believed that herbal products were more efficacious and safer (61.02%) than orthodox medicines; with almost all of them (94.92%) acknowledging the beneficial effects of incorporating herbal medicines into orthodox medicine practice. However, most of them (72.88%) confessed having little knowledge on herbal remedies, especially drug‑herbs interactions (81.36%), and their main source of information on herbs was from school (56.50%). Conclusions: The result showed poor level of pharmacists’ knowledge on herbal medicine; which might result in poor patients’ counseling on herbal therapy, especially regarding their safety and potential interaction with orthodox medicine.
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    Psychometric Classical Theory Test and Item Response Theory Validation of Patients’ Knowledge, Attitudes and Practices of Uncomplicated Malaria Instrument
    (Journal of Young Pharmacists, 2019) Nanloh Samuel Jimam; Sohail Ahmad; Nahlah Elkudssiah Ismail
    To develop and validate Patients’ Knowledge, Attitudes and Practices Instrument for Uncomplicated Malaria (PKAPIUM) through Classical Test Theory (CTT) complemented by Items Response Theory (IRT). Methods: A draft 31-items’ scale was developed using relevant variables from literature and initially screened by six experts before it was used to collect data from 300 patients receiving treatment for uncomplicated malaria in Primary Health Care (PHC) facilities in Plateau state, Nigeria. An orchestrated classical and modern psychometric approach including CTT and IRT was then used to validate the draft instrument through IBM® Statistical Package for Social Sciences (SPSS®) version 23 and Analysis of Moment Structures (AMOS™) software version 22 and Bond and Fox software ®, respectively. Results: The 31-items’ draft scale showed good Item’s Content Validity Index (I-CVI) (> 0.8) with good Universal Agreement (UA) level of Scale Content Validity Index (S-CVI/UA) (0.9 – 1) and average CVI(S-CVI/Ave) (0.98 – 1). The CTT and Rasch analyses resulted in retention of twenty one items distributed under Knowledge, Attitude and Practice (KAP) constructs, with Average Variance Extracted (AVE), square root AVE,
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    Assessment of the knowledge and attitude of Jos residents toward the prevention and treatment of fever
    (Medical Journal of Dr. D.Y. Patil University |, 2019-09-04) Jimam S. Nanloh,; Galam Z. Nanyak1; Dangiwa A. Dauda
    A fever is a temporary increase in the body temperature, indicating that something out of the ordinary is going on in the body. Fever is a common sign of changes in the body of patients and a common cause of hospital visits, especially for children. Occurrence of fever in most cases is due to self-limiting viral infection or serious bacterial or other microbial infections. Aim: The study is aimed at assessing the current level of knowledge and attitudes of Jos residents about what fever is all about, its treatment and prevention. Materials and Methods: The study was cross-sectional in design, which involved a two-stage cluster random sampling procedure. Jos is divided into districts and in each districts, the area was broken down to sub-districts from which three zones where selected; based on population within the selected zones, households were randomly numbered and houses assigned odd number were identified. A semi structured interviewer questionnaire was then administered to the respondents and the finally filled questionnaires were then retrieved and analyzed using the SPSS version 20.0 software programmer. Result: Out of the 400 respondents, 66.5% falls within the age range of 21-49 years with females constituting 56.5% of the study population. Educationally, 45.9% of the respondents had completed secondary schools while 39.6% had bachelor degree. 67.2% of the respondents agreed that malaria was the common conditions that come with fever, followed by typhoid fever (19%). 26.5% of the respondents agreed that personal preventive/environmental hygiene remain the mainstay when it comes to fever prevention, with 26.5% also believing that the use of pesticides/rodenticides was another preventive measure, whereas 20.6% agreed that chemoprophylaxis was another option. Conclusion: The study showed that the residence of Jos had good knowledge of conditions that are associated with fever and its management, which might be due to the literacy levels of the study population; there is still need to improve their knowledge on the other conditions that comes with fever and their preventive measures
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    Breast cancer in Jos, Nigeria: An audit on knowledge, attitude, and practices
    (2017-02-21) Nanloh S. Jimam; Shalkur David; Gboluwaga O. Ejisun
    Objectives: The main purpose of the study was to assess the knowledge, attitudes, and practices of women concerning breast cancer in Jos and environs. Methods: A semi‑structured questionnaire was administered to 400 respondents within the age of 18 years and above residing in Jos North and South Local Government Areas of Plateau state. The data collected were then analyzed using the IBM Statistical Package for Social Sciences version 20.0 software programmer. Results: Out of the 400 study populations, only 395 (98.8%) responded to the study and 209 (53.0%) of them fall within the age 18–27 years while 89 (22.6%) were within 28 and 37 years, with only 17.8% and 6.6% in the age groups of 38–47 and ≥48 years, respectively. Two hundred and twenty (55.6%) were single, 153 (38.8%) married, while 8 (2.3%) divorced/separated, and 11 (2.8%) were widowed. The highest number (172 [43.7%]) of the respondents had secondary certificates as their highest academic qualifications, followed by diploma/ The Nigeria Certificate in Education/Community Health Extension Workers (25.1%) and first degree (20.8%). Nearly 95% of the respondents have heard of breast cancer, with 30.94% of them having knowledge of the risk factors, 59.9% knew the signs and symptoms of the disease, and their main source of information (35.8%) was the media. Most of the respondents had positive attitude toward the disease, but their cancer breast screening practices were generally poor as majority of them (47.1%) had no idea of the right age to initiate self‑breast examination, with majority (28.4%) confessing not practicing self‑breast examination very often, neither visiting medical practitioner for breast cancer examination and care. Conclusion: The result of this study shows positive attitudes of the respondents toward the disease though high percentage of them had poor knowledge on risk factors and average knowledge of the signs and symptoms of the disease, in addition to poor breast self‑examination practices. Key Words: Breast cancer, knowledge, attitudes, and practices, risk factors, self‑breast examination