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Prevalence of some metals in native and branded factory-based lager beers within Jos metropolis
(2015-12) S Y. Gazuwa; J D Dabak; G A Ubom
Ethyl alcohol toxicity is implicated in disease conditions such as cirrhosis, hepatitis and these ailments among drinkers are high even after seeking medical attention. This work was therefore undertaken to analyse for zinc, iron, lead, cadmium, and manganese as contaminants in samples of beers. Atomic absorption spectrophotometric technique was applied to achieve the objectives of the work. Although the results indicated contamination of the samples with the metals, the magnitude of the contamination was higher in native, relative the factory-based lager beers. In burukutu, the level of Zn was above that in pito and goskolo. Compared to the maximum reference levels in drinking water, level of Fe was lower just as for Pb (P >0.05). Goskolo had the highest burden of Cd followed by burukutu and pito. In burukutu and pito, Mn was high (P =0.05) compared to reference values. In the case of the factory-based lager beers, levels of Zn, Mn and Fe were below the reference values for all the brands. Levels of Cd and Pb were above the maximum values (P =0.05). In Guinness, Harp, and Star, the content of Cd and Pb were significantly (P =0.05) above reference values for drinking water, but other metals were not significant (P >0.05). Extent of contamination with Pb was highest in Gulder (P=0.05). Alcoholic drinks are contaminated with metals whose toxicities could aggravate ailments, usually ascribed to alcohol alone, in drinkers.
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Inflammatory breast cancer: Still a diagnostic dilemma
(Journal of Surgery, 2014-06-10) M. A. Misauno; W. M. Isichei
Background: Inflammatory breast cancer (IBC) is a rapidly progressive disease associated with high mortality in developing countries. The patients are managed for mastitis’s first and IBC becomes a diagnosis of exclusion after failed response to appropriate antibiotic therapy. This study was aimed at evaluating the outcome of management of IBC in North central Nigeria. Patients and method: This was a prospective analysis of consecutive patients presenting with breast cancer at the Abubakar Tafawa Balewa University teaching hospital Bauchi (ATBUTH) from January 2011 to December 2012. Results: A total of 52 breast cancers were managed, mean age was 31+/- 2years with an age range of 29 -33 years. There were 51 females and 1male (f: m = 51:1). IBC accounted for 9(17.3 %) of the breast cancers. Conclusion: IBC is frequently misdiagnosed as mastitis for various reasons and a high index of suspicion is required to clinch the diagnosis.
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THE EFFECT OF RICINUS COMMUNIS-LINN (RICOM 1013-J) ON SEMEN PARAMETERS: A COMPARATIVE STUDY
(JPCS, 2011-04) Ekwere Okon Ekwere; Francis Kanayo Okwuasaba3; Rosaleen Thecla McNeil
Objectives: The seed variety of Ricinus communis-linn (RICOM 1013-J) is a popular contraceptive agent among the Rukuba women of Central Nigeria. The aim of this study is to compare the effect of RICOM 1013-J to that of an anti-androgen, diane-35 (which contains 0.035g cyproterone acetate and 2mg of ethinyl oestradiol), on testicular histology and function. Material and Methods: Adult male Wistar rats weighing 200-250g were used for this experiment. The animals were administered orally with 0.41mg/kg of diane-35, RICOM 1013-J (10mg/kg) and10mg/kg of normal physiological saline, for the control group. The rats were then weighed weekly for six weeks. Results and Conclusions: The semen parameters measured showed marked suppression of testicular function in the groups treated with RICOM 1013-J and diane-35, when compared to that of the control. It can therefore be concluded that RICOM 1013-J suppresses testicular histology and function and is a potential male contraceptive agent.
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Geochemical Effects Of Mineralization In Arufu Area NE Nigeria: Implication On Human Health
(INTERNATIONAL JOURNAL OF INNOVATIVE RESEARCH & DEVELOPMENT, 2013-10) Ekeleme I. Aquila; Uzoegbu M. Uche; Olorunyomi A. Enoch
The sulphide mineralization in Arufu and environs, northeastern Nigeria was investigated with the view of determining the concentrations of selected trace elements in soils, to examine the mineralization potential and their possible health implications. The stratigraphy of the study area shows a dominance of altered carbonates of the Asu River Group which also hosts the mineralization and some outcrops of gneisses. Fifty soil and stream samples were analysed using the Inductively Coupled Plasma – Optical Emission Spectroscopy (ICP-OES) technique. The values for the concentrations of some selected elements ranges from; As(0 - 97.19ppm), Cd(0 - 4.653ppm), Co(0 - 503.2ppm), Cr(4.401 - 6020ppm), Cu(0 - 74.77ppm), Ni(0 - 24560ppm), Pb(3.357 - 59660ppm), S(0 - 4469ppm). Multiple correlation and regression analysis of the geochemical data showed a relationship between Pb and As and significant regression of Pb on As and Cd. The results of the Index of geoaccumulation (Igeo), Contamination Factor (CF) and Degree of Contamination (Cdeg) indicate moderate to high Pb and As contamination. The values obtained indicates As, Pb and Cd have concentrations above the maximum permitted levels of 0.01ppm, 0.01ppm and 0.003ppm respectively in water for human consumption, and above the threshold of contamination of 15ppm and 20ppm for As and Pb respectively. This suggests that more people will be at risk of pollutants as lead – zinc exploitation proceeds. The frequency distribution plots of the elements generally show unimodal distribution indicating that most of the elements belong to a common parent material.
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KNOWLEDGE, ATTITIUDE AND PRACTICE TOWOARDS HYPERTENTION SCREENING AND NON DRUG CONTROL MEASURES AMONG ADMINISTRATUIVE STAFF OF UNIVERSITY OF JOS
(2017-07) DANIEL CLETUS;RN,REN, RPHN,BSC MSC PHD;; OYEDELE EMMANUEL A RN, BSc, MSc
The prevalence of hypertension is on the rise globally leading to high morbidity, this descriptive study assessed knowledge, attitude and practice of high blood pressures, non drug and drug control measures among administrative staff