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    Prevalence of Hepatitis B Surface Antigen (HBsAg) and Hepatitis B Antibodies among Commercial Motor Park Workers in Jos North, Nigeria
    (Saudi Journal of Pathology and Microbiology, 2019-03-31) Nkup Jude Yunzoom; Ocheme Julius; Sule Jesinta; David Samirah; Cirfat Nanya; Otobo Innocent; Anejo-Okopi Joseph
    Although there are several reports on the prevalence of HBsAg in Nigeria, there is paucity of data on the prevalence of HBsAg and HBAb among motor park workers in the country. Objective: This study aimed to determine the seroprevalence and risk factors among commercial Motor park workers in Jos, Nigeria. Methods: One hundred and thirty one (131) commercially motor park Workers who consented to take part in this study were recruited. Aseptically, 5ml of venous blood was collected from each participant and screened for HBsAg and HBAbs markers using one step, rapid chromatographic immunoassay and associated risk factors using structured questionnaire which was voluntarily completed by the participants and the data were thereafter analysed. Results: Of the 131 participants, 105 were males and 26 females with age range between 16-75 years. An overall HBsAg seropositivity of 16.8% and HBAbs positivity of 74.8% were observed. On multivariate analysis, factors such as multiple sexual partners: HBsAg (35.0%), anti-HBs (10.0%), anti-HBe (20.0%) and anti-HBc (35.0%); history of surgery: HBsAg (64.3%), anti-HBs (21.4%), anti-HBe (7.1%) and anti-HBc (7.1); lack of condom usage: HBsAg (15.7%) anti-HBs (28.7%), anti-HBe (18.3%) and anti-HBc (27.8%) were among some determinants of HBV infection in this study. Conclusion: The data results suggest high prevalence of HBV among this mobile group of people;, and with the increasing number of individuals and corporate bodies engaged in one or more activities at motor parks, there is the need for deliberate efforts for preventive measures.
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    Prevalence of Cryptosporidium Infection among HIV-1 Infected Adult Patients Attending Jos University Teaching Hospital, Jos, Nigeria
    (UMYU Journal of Microbiology Research, 2017-06-01) Anejo-Okopi, A. Joseph; Ejeliogu, U. Emeka; Gomerep, Simji; Okojokwu, O. Julius; Okechalu, Juliet; Oguchukwu, C. Sandra; Lar, M. Patricia
    Cryptosporidium is a leading cause of chronic diarrhea in HIV-1infected patients, but there is paucity of data on the prevalence of Cryptosporidium and factors associated with the infection. We determined the prevalence and factors associated with Cryptosporidium infection among HIV-1 infected adult patients at Jos University Teaching hospital, Jos, Nigeria. A cross-sectional study in which a total of 296 fecal specimens from HIV-1 infected patients with diarrhea was collected and structured questionnaire was used to collect demographic and clinical data. The fecal samples were examined for Cryptosporidium by formal-ether concentration and modified Ziehl-Neelsen staining technique, and the oocysts identified by microscopy. Two hundred and ninety six fecal samples where analyze from156 (52.7%) females and 140(47.3%) males. The prevalence of Cryptosporidium infection among HIV-1 infected patients was 4.7%. Among females 9 (5.8%) had Cryptosporidium infection while (5)3.6% in males; P=0.696. The age group 21-30 years had the highest prevalence of (8)10.0%. A statistically significant association of Cryptosporidium infection was observed with rural type of residence, P=0.046. In conclusion the prevalence of Cryptosporidium infection among HIV-1 infected adult patients with diarrhea was low. This may be due to early commencement of antiretroviral drugs and the use of anti-parasitic prophylaxis among the patients. Further larger studies on the molecular identification of the species of Cryptosporidium are needed to determine the available zoonotic strains.